La tua domanda è sbagliata:prova questo
SELECT Comment1, Comment2, Comment3, Comment4
FROM Students
WHERE Course1 = '$value1' AND Course2 = '$value1'
AND Course3 = '$value1' AND Course4 = '$value1'
O
SELECT Comment1, Comment2, Comment3, Comment4
FROM Students
WHERE Course1 = '$value1' OR Course2 = '$value1'
OR Course3 = '$value1' OR Course4 = '$value1'
In base alle tue esigenze, usa AND o OR durante il controllo del corso
